Generation of Five Human Lactoferrin Transgenic Cloned Goats Using Fibroblast Cells and Their Methylation Status of Putative Differential Methylation Regions of IGF2R and H19 Imprinted Genes

BACKGROUND: Somatic cell nuclear transfer (SCNT) is a promising technique to produce transgenic cloned mammalian, including transgenic goats which may produce Human Lactoferrin (hLF). However, success percentage of SCNT is low, because of gestational and neonatal failure of transgenic embryos. Accor...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Li, Wan, Yongjie, Sun, Yanyan, Zhang, Yanli, Wang, Ziyu, Song, Yang, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813735/
https://www.ncbi.nlm.nih.gov/pubmed/24204972
http://dx.doi.org/10.1371/journal.pone.0077798

Ejemplares similares

Ejemplares similares