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Hematoporphyrin Monomethyl Ether-Mediated Photodynamic Therapy Selectively Kills Sarcomas by Inducing Apoptosis

We investigated the antitumor effect and mechanism of hematoporphyrin monomethyl ether-mediated photodynamic therapy (HMME-PDT) in sarcomas. Intracellular uptake of HMME by osteosarcoma cells (LM8 and K7) was time- and dose-dependent, while this was not observed for myoblast cells (C2C12) and fibrob...

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Detalles Bibliográficos
Autores principales: Zeng, Hui, Sun, Mengxiong, Zhou, Chenghao, Yin, Fei, Wang, Zhuoying, Hua, Yingqi, Cai, Zhengdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813767/
https://www.ncbi.nlm.nih.gov/pubmed/24204937
http://dx.doi.org/10.1371/journal.pone.0077727