A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)

Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the growth and progression of tumors. Epithelial-mesenchymal transition (EMT) is pivotal in malignant tumor progression and VM formation. With increasing knowledge of cancer stem cell (CSC) phenotypes and functions,...

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Detalles Bibliográficos
Autores principales: FAN, YUN-LONG, ZHENG, MIN, TANG, YA-LING, LIANG, XIN-HUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813799/
https://www.ncbi.nlm.nih.gov/pubmed/24179490
http://dx.doi.org/10.3892/ol.2013.1555
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author FAN, YUN-LONG
ZHENG, MIN
TANG, YA-LING
LIANG, XIN-HUA
author_facet FAN, YUN-LONG
ZHENG, MIN
TANG, YA-LING
LIANG, XIN-HUA
author_sort FAN, YUN-LONG
collection PubMed
description Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the growth and progression of tumors. Epithelial-mesenchymal transition (EMT) is pivotal in malignant tumor progression and VM formation. With increasing knowledge of cancer stem cell (CSC) phenotypes and functions, increasing evidence suggests that CSCs are involved in VM formation. Recent studies have indicated that EMT is relevant to the acquisition and maintenance of stem cell-like characteristics. Thus, in this review we discuss the correlation between CSCs, EMT and VM formation.
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spelling pubmed-38137992013-10-31 A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review) FAN, YUN-LONG ZHENG, MIN TANG, YA-LING LIANG, XIN-HUA Oncol Lett Articles Vasculogenic mimicry (VM), a new pattern of tumor microcirculation, is important for the growth and progression of tumors. Epithelial-mesenchymal transition (EMT) is pivotal in malignant tumor progression and VM formation. With increasing knowledge of cancer stem cell (CSC) phenotypes and functions, increasing evidence suggests that CSCs are involved in VM formation. Recent studies have indicated that EMT is relevant to the acquisition and maintenance of stem cell-like characteristics. Thus, in this review we discuss the correlation between CSCs, EMT and VM formation. D.A. Spandidos 2013-11 2013-08-30 /pmc/articles/PMC3813799/ /pubmed/24179490 http://dx.doi.org/10.3892/ol.2013.1555 Text en Copyright © 2013, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
FAN, YUN-LONG
ZHENG, MIN
TANG, YA-LING
LIANG, XIN-HUA
A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
title A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
title_full A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
title_fullStr A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
title_full_unstemmed A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
title_short A new perspective of vasculogenic mimicry: EMT and cancer stem cells (Review)
title_sort new perspective of vasculogenic mimicry: emt and cancer stem cells (review)
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813799/
https://www.ncbi.nlm.nih.gov/pubmed/24179490
http://dx.doi.org/10.3892/ol.2013.1555
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