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Counteracting the activation of pAkt by inhibition of MEK/Erk inhibition reduces actin disruption-mediated apoptosis in PTEN-null PC3M prostate cancer cell lines

The actin cytoskeleton is important in the maintenance of cellular homeostasis and in signal transduction pathways leading to cell growth and apoptotic cell death in eukaryotic cells. Disruption of actin dynamics is associated with morphological changes in cancer cells. Deletion of phosphatase and t...

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Detalles Bibliográficos
Autores principales:	AHN, YONG-TAE, SHIN, IK JAE, KIM, JONG-MYOUNG, KIM, YOUN SOOK, LEE, CHU, JU, SEONG-A., AN, WON G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813806/ https://www.ncbi.nlm.nih.gov/pubmed/24179529 http://dx.doi.org/10.3892/ol.2013.1547

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