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Molecular Characterization of Lys49 and Asp49 Phospholipases A(2) from Snake Venom and Their Antiviral Activities against Dengue virus

We report the detailed molecular characterization of two PLA(2)s, Lys49 and Asp49 isolated from Bothrops leucurus venom, and examined their effects against Dengue virus (DENV). The Bl-PLA(2)s, named BlK-PLA(2) and BlD-PLA(2), are composed of 121 and 122 amino acids determined by automated sequencing...

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Detalles Bibliográficos
Autores principales: Cecilio, Alzira B., Caldas, Sergio, De Oliveira, Raiana A., Santos, Arthur S. B., Richardson, Michael, Naumann, Gustavo B., Schneider, Francisco S., Alvarenga, Valeria G., Estevão-Costa, Maria I., Fuly, Andre L., Eble, Johannes A., Sanchez, Eladio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813911/
https://www.ncbi.nlm.nih.gov/pubmed/24131891
http://dx.doi.org/10.3390/toxins5101780