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Toward a Molecular Classification of Colorectal Cancer: The Role of Microsatellite Instability Status

Microsatellite instability (MSI) is the molecular hallmark of DNA mismatch repair deficiency. Since its initial description in colorectal cancer (CRC) in 1993 and its association with Lynch syndrome, the most common inherited cancer predisposition world-wide, accumulating evidence suggests that MSI...

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Detalles Bibliográficos
Autor principal: Heinimann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814007/
https://www.ncbi.nlm.nih.gov/pubmed/24199172
http://dx.doi.org/10.3389/fonc.2013.00272