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DNA Damage in Rheumatoid Arthritis: An Age-Dependent Increase in the Lipid Peroxidation-Derived DNA Adduct, Heptanone-Etheno-2′-Deoxycytidine

Objective. To evaluate what types of DNA damages are detected in rheumatoid arthritis (RA). Methods. The DNA adducts such as 8-oxo-hydroxy-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG), 1,N(6)-etheno-2′-deoxyadenosine (εdA), and heptanone-etheno-2′-deoxycytidine (HεdC) in genomic DNAs, derived from whole...

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Detalles Bibliográficos
Autores principales:	Ogawa, Masako, Matsuda, Tomonari, Ogata, Atsushi, Hamasaki, Toshimitsu, Kumanogoh, Atsushi, Toyofuku, Toshihiko, Tanaka, Toshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814043/ https://www.ncbi.nlm.nih.gov/pubmed/24222845 http://dx.doi.org/10.1155/2013/183487

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