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The degradation of airway tight junction protein under acidic conditions is probably mediated by transient receptor potential vanilloid 1 receptor

Acidic airway microenvironment is one of the representative pathophysiological features of chronic inflammatory respiratory diseases. Epithelial barrier function is maintained by TJs (tight junctions), which act as the first physical barrier against the inhaled substances and pathogens of airway. As...

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Detalles Bibliográficos
Autores principales: Xu, Rui, Li, Qi, Zhou, Jia, Zhou, Xiang-dong, Perelman, Juliy M., Kolosov, Victor P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814059/
https://www.ncbi.nlm.nih.gov/pubmed/24073800
http://dx.doi.org/10.1042/BSR20130087

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