Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus

Liraglutide is a glucagon-like peptide 1 (GLP-1) analog indicated for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise in adults. Liraglutide lowers blood glucose levels by stimulating insulin secretion and decreasing glucagon release in glucose-dependent manners, increas...

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Detalles Bibliográficos
Autores principales: Micale, Sara J., Kane, Michael P., Hogan, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814067/
https://www.ncbi.nlm.nih.gov/pubmed/24222881
http://dx.doi.org/10.1155/2013/703925
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author Micale, Sara J.
Kane, Michael P.
Hogan, Eileen
author_facet Micale, Sara J.
Kane, Michael P.
Hogan, Eileen
author_sort Micale, Sara J.
collection PubMed
description Liraglutide is a glucagon-like peptide 1 (GLP-1) analog indicated for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise in adults. Liraglutide lowers blood glucose levels by stimulating insulin secretion and decreasing glucagon release in glucose-dependent manners, increases satiety, and delays gastric emptying. Liraglutide, unlike metformin and insulin, is not approved for use in the pediatric population. We report the successful off-label use of liraglutide in an obese, 16 year old Caucasian female with type 2 diabetes mellitus.
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spelling pubmed-38140672013-11-11 Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus Micale, Sara J. Kane, Michael P. Hogan, Eileen Case Rep Pediatr Case Report Liraglutide is a glucagon-like peptide 1 (GLP-1) analog indicated for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise in adults. Liraglutide lowers blood glucose levels by stimulating insulin secretion and decreasing glucagon release in glucose-dependent manners, increases satiety, and delays gastric emptying. Liraglutide, unlike metformin and insulin, is not approved for use in the pediatric population. We report the successful off-label use of liraglutide in an obese, 16 year old Caucasian female with type 2 diabetes mellitus. Hindawi Publishing Corporation 2013 2013-10-03 /pmc/articles/PMC3814067/ /pubmed/24222881 http://dx.doi.org/10.1155/2013/703925 Text en Copyright © 2013 Sara J. Micale et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Micale, Sara J.
Kane, Michael P.
Hogan, Eileen
Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus
title Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus
title_full Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus
title_fullStr Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus
title_full_unstemmed Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus
title_short Off-Label Use of Liraglutide in the Management of a Pediatric Patient with Type 2 Diabetes Mellitus
title_sort off-label use of liraglutide in the management of a pediatric patient with type 2 diabetes mellitus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814067/
https://www.ncbi.nlm.nih.gov/pubmed/24222881
http://dx.doi.org/10.1155/2013/703925
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AT hoganeileen offlabeluseofliraglutideinthemanagementofapediatricpatientwithtype2diabetesmellitus

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