Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β

Mammary tumorigenesis and epithelial–mesenchymal transition (EMT) programs cooperate in converting transforming growth factor-β (TGF-β) from a suppressor to a promoter of breast cancer metastasis. Although previous reports associated β1 and β3 integrins with TGF-β stimulation of EMT and metastasis,...

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Detalles Bibliográficos
Autores principales: Parvani, Jenny G., Galliher-Beckley, Amy J., Schiemann, Barbara J., Schiemann, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814150/
https://www.ncbi.nlm.nih.gov/pubmed/24006485
http://dx.doi.org/10.1091/mbc.E12-10-0776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814150/
https://www.ncbi.nlm.nih.gov/pubmed/24006485
http://dx.doi.org/10.1091/mbc.E12-10-0776

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