Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

Despite substantial efforts to understand the interactions between nanoparticles and cells, the cellular processes that determine the efficiency of intracellular drug delivery remain largely unclear. Here we examined cellular uptake of siRNA delivered in lipid nanoparticles (LNPs) using cellular tra...

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Detalles Bibliográficos
Autores principales: Sahay, Gaurav, Querbes, William, Alabi, Christopher, Eltoukhy, Ahmed, Sarkar, Sovan, Zurenko, Christopher, Karagiannis, Emannouil, Love, Kevin, Chen, Delai, Zoncu, Roberto, Buganim, Yosef, Schroeder, Avi, Langer, Robert, Anderson, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814166/
https://www.ncbi.nlm.nih.gov/pubmed/23792629
http://dx.doi.org/10.1038/nbt.2614

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