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Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies
BACKGROUND: We conducted a dosimetric comparison of an ipsilateral beam arrangement for intensity modulated radiotherapy (IMRT) with off-axis beams. PATIENTS AND METHODS: Six patients who received post-operative radiotherapy (RT) for parotid malignancies were used in this dosimetric study. Four trea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Versita, Warsaw
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814288/ https://www.ncbi.nlm.nih.gov/pubmed/24294188 http://dx.doi.org/10.2478/raon-2013-0010 |
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author | Yirmibesoglu, Eda Fried, David V. Kostich, Mark Rosenman, Julian Shockley, William Weissler, Mark Zanation, Adam Chera, Bhishamjit |
author_facet | Yirmibesoglu, Eda Fried, David V. Kostich, Mark Rosenman, Julian Shockley, William Weissler, Mark Zanation, Adam Chera, Bhishamjit |
author_sort | Yirmibesoglu, Eda |
collection | PubMed |
description | BACKGROUND: We conducted a dosimetric comparison of an ipsilateral beam arrangement for intensity modulated radiotherapy (IMRT) with off-axis beams. PATIENTS AND METHODS: Six patients who received post-operative radiotherapy (RT) for parotid malignancies were used in this dosimetric study. Four treatment plans were created for each CT data set (24 plans): 1) ipsilateral 4-field off-axis IMRT (4fld-OA), 2) conventional wedge pair (WP), 3) 7 field co-planar IMRT (7fld), and 4) ipsilateral co-planar 4-field quartet IMRT (4fld-CP). Dose, volume statistics for the planning target volumes (PTVs) and planning risk volumes (PRVs) were compared for the four treatment techniques. RESULTS: Wedge pair plans inadequately covered the deep aspect of the PTV. The 7-field IMRT plans delivered the largest low dose volumes to normal tissues. Mean dose to the contralateral parotid was highest for 7 field IMRT. Mean dose to the contralateral submandibular gland was highest for 7 field IMRT and WP. 7 field IMRT plans had the highest dose to the oral cavity. The mean doses to the brainstem, spinal cord, ipsilateral temporal lobe, cerrebellum and ipsilateral cochlea were similar among the four techniques. CONCLUSIONS: For postoperative treatment of the parotid bed, 4-field ipsilateral IMRT techniques provided excellent coverage while maximally sparing the contralateral parotid gland and submandibular gland. |
format | Online Article Text |
id | pubmed-3814288 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Versita, Warsaw |
record_format | MEDLINE/PubMed |
spelling | pubmed-38142882013-12-01 Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies Yirmibesoglu, Eda Fried, David V. Kostich, Mark Rosenman, Julian Shockley, William Weissler, Mark Zanation, Adam Chera, Bhishamjit Radiol Oncol Research Article BACKGROUND: We conducted a dosimetric comparison of an ipsilateral beam arrangement for intensity modulated radiotherapy (IMRT) with off-axis beams. PATIENTS AND METHODS: Six patients who received post-operative radiotherapy (RT) for parotid malignancies were used in this dosimetric study. Four treatment plans were created for each CT data set (24 plans): 1) ipsilateral 4-field off-axis IMRT (4fld-OA), 2) conventional wedge pair (WP), 3) 7 field co-planar IMRT (7fld), and 4) ipsilateral co-planar 4-field quartet IMRT (4fld-CP). Dose, volume statistics for the planning target volumes (PTVs) and planning risk volumes (PRVs) were compared for the four treatment techniques. RESULTS: Wedge pair plans inadequately covered the deep aspect of the PTV. The 7-field IMRT plans delivered the largest low dose volumes to normal tissues. Mean dose to the contralateral parotid was highest for 7 field IMRT. Mean dose to the contralateral submandibular gland was highest for 7 field IMRT and WP. 7 field IMRT plans had the highest dose to the oral cavity. The mean doses to the brainstem, spinal cord, ipsilateral temporal lobe, cerrebellum and ipsilateral cochlea were similar among the four techniques. CONCLUSIONS: For postoperative treatment of the parotid bed, 4-field ipsilateral IMRT techniques provided excellent coverage while maximally sparing the contralateral parotid gland and submandibular gland. Versita, Warsaw 2013-10-08 /pmc/articles/PMC3814288/ /pubmed/24294188 http://dx.doi.org/10.2478/raon-2013-0010 Text en Copyright © by Association of Radiology & Oncology http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Research Article Yirmibesoglu, Eda Fried, David V. Kostich, Mark Rosenman, Julian Shockley, William Weissler, Mark Zanation, Adam Chera, Bhishamjit Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
title | Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
title_full | Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
title_fullStr | Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
title_full_unstemmed | Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
title_short | Dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
title_sort | dosimetric evaluation of an ipsilateral intensity modulated radiotherapy beam arrangement for parotid malignancies |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814288/ https://www.ncbi.nlm.nih.gov/pubmed/24294188 http://dx.doi.org/10.2478/raon-2013-0010 |
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