Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Previous studies in narcolepsy, an autoimmune disorder affecting hypocretin (orexin) neurons and recently associated with H1N1 influenza, have demonstrated significant associations with five loci. Using a well-characterized Chinese cohort, we refined known associations in TRA@ and P2RY11-DNMT1 and i...

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Detalles Bibliográficos
Autores principales: Han, Fang, Faraco, Juliette, Dong, Xiao Song, Ollila, Hanna M., Lin, Ling, Li, Jing, An, Pei, Wang, Shan, Jiang, Ke Wei, Gao, Zhan Cheng, Zhao, Long, Yan, Han, Liu, Ya Nan, Li, Qing Hua, Zhang, Xiao Zhe, Hu, Yan, Wang, Jing Yu, Lu, Yun Hui, Lu, Chang Jun, Zhou, Wei, Hallmayer, Joachim, Huang, Yu Shu, Strohl, Kingman P., Pollmächer, Thomas, Mignot, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814311/
https://www.ncbi.nlm.nih.gov/pubmed/24204295
http://dx.doi.org/10.1371/journal.pgen.1003880

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