Cargando…
PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth
In multicellular organisms, tight regulation of gene expression ensures appropriate tissue and organismal growth throughout development. Reversible phosphorylation of the RNA Polymerase II (RNAPII) C-terminal domain (CTD) is critical for the regulation of gene expression states, but how phosphorylat...
Autores principales: | Ciurciu, Anita, Duncalf, Louise, Jonchere, Vincent, Lansdale, Nick, Vasieva, Olga, Glenday, Peter, Rudenko, Andreii, Vissi, Emese, Cobbe, Neville, Alphey, Luke, Bennett, Daimark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814315/ https://www.ncbi.nlm.nih.gov/pubmed/24204300 http://dx.doi.org/10.1371/journal.pgen.1003885 |
Ejemplares similares
-
Drosophila Uri, a PP1α binding protein, is essential for viability, maintenance of DNA integrity and normal transcriptional activity
por: Kirchner, Jasmin, et al.
Publicado: (2008) -
Drosophila USP22/nonstop polarizes the actin cytoskeleton during collective border cell migration
por: Badmos, Hammed, et al.
Publicado: (2021) -
Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene
por: Jonchere, Vincent, et al.
Publicado: (2013) -
MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
por: Dingar, Dharmendra, et al.
Publicado: (2018) -
The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase
por: Wei, Yong, et al.
Publicado: (2022)