High Throughput Sequencing Reveals Alterations in the Recombination Signatures with Diminishing Spo11 Activity

Spo11 is the topoisomerase-like enzyme responsible for the induction of the meiosis-specific double strand breaks (DSBs), which initiates the recombination events responsible for proper chromosome segregation. Nineteen PCR-induced alleles of SPO11 were identified and characterized genetically and cy...

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Detalles Bibliográficos
Autores principales: Rockmill, Beth, Lefrançois, Philippe, Voelkel-Meiman, Karen, Oke, Ashwini, Roeder, G. Shirleen, Fung, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814317/
https://www.ncbi.nlm.nih.gov/pubmed/24204324
http://dx.doi.org/10.1371/journal.pgen.1003932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814317/
https://www.ncbi.nlm.nih.gov/pubmed/24204324
http://dx.doi.org/10.1371/journal.pgen.1003932

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