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High Throughput Sequencing Reveals Alterations in the Recombination Signatures with Diminishing Spo11 Activity
Spo11 is the topoisomerase-like enzyme responsible for the induction of the meiosis-specific double strand breaks (DSBs), which initiates the recombination events responsible for proper chromosome segregation. Nineteen PCR-induced alleles of SPO11 were identified and characterized genetically and cy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814317/ https://www.ncbi.nlm.nih.gov/pubmed/24204324 http://dx.doi.org/10.1371/journal.pgen.1003932 |