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Nuclear Fragile X Mental Retardation Protein Is localized to Cajal Bodies
Fragile X syndrome is caused by loss of function of a single gene encoding the Fragile X Mental Retardation Protein (FMRP). This RNA-binding protein, widely expressed in mammalian tissues, is particularly abundant in neurons and is a component of messenger ribonucleoprotein (mRNP) complexes present...
Autores principales: | Dury, Alain Y., El Fatimy, Rachid, Tremblay, Sandra, Rose, Timothy M., Côté, Jocelyn, De Koninck, Paul, Khandjian, Edouard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814324/ https://www.ncbi.nlm.nih.gov/pubmed/24204304 http://dx.doi.org/10.1371/journal.pgen.1003890 |
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