Mycobacterium tuberculosis Type VII Secreted Effector EsxH Targets Host ESCRT to Impair Trafficking

Mycobacterium tuberculosis (Mtb) disrupts anti-microbial pathways of macrophages, cells that normally kill bacteria. Over 40 years ago, D'Arcy Hart showed that Mtb avoids delivery to lysosomes, but the molecular mechanisms that allow Mtb to elude lysosomal degradation are poorly understood. Spe...

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Detalles Bibliográficos
Autores principales: Mehra, Alka, Zahra, Aleena, Thompson, Victor, Sirisaengtaksin, Natalie, Wells, Ashley, Porto, Maura, Köster, Stefan, Penberthy, Kristen, Kubota, Yoshihisha, Dricot, Amelie, Rogan, Daniel, Vidal, Marc, Hill, David E., Bean, Andrew J., Philips, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814348/
https://www.ncbi.nlm.nih.gov/pubmed/24204276
http://dx.doi.org/10.1371/journal.ppat.1003734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814348/
https://www.ncbi.nlm.nih.gov/pubmed/24204276
http://dx.doi.org/10.1371/journal.ppat.1003734

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