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Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ

RlmJ catalyzes the m(6)A2030 methylation of 23S rRNA during ribosome biogenesis in Escherichia coli. Here, we present crystal structures of RlmJ in apo form, in complex with the cofactor S-adenosyl-methionine and in complex with S-adenosyl-homocysteine plus the substrate analogue adenosine monophosp...

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Detalles Bibliográficos
Autores principales:	Punekar, Avinash S., Liljeruhm, Josefine, Shepherd, Tyson R., Forster, Anthony C., Selmer, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814359/ https://www.ncbi.nlm.nih.gov/pubmed/23945937 http://dx.doi.org/10.1093/nar/gkt719

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