Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function

Expression of the complete HIV-1 genome depends on the appropriate processing of viral RNA. Altering the balance of viral RNA processing impairs replication of the virus. In this report, we characterize two small molecule modulators of HIV-1 RNA processing, 8-azaguanine and 2-(2-(5-nitro-2-thienyl)v...

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Detalles Bibliográficos
Autores principales: Wong, Raymond W., Balachandran, Ahalya, Haaland, Matthew, Stoilov, Peter, Cochrane, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814367/
https://www.ncbi.nlm.nih.gov/pubmed/23945945
http://dx.doi.org/10.1093/nar/gkt727

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