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Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t(6)A tRNA modification

N(6)-threonylcarbamoyladenosine (t(6)A) is a universal tRNA modification essential for normal cell growth and accurate translation. In Archaea and Eukarya, the universal protein Sua5 and the conserved KEOPS/EKC complex together catalyze t(6)A biosynthesis. The KEOPS/EKC complex is composed of Kae1,...

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Detalles Bibliográficos
Autores principales:	Perrochia, Ludovic, Guetta, Dorian, Hecker, Arnaud, Forterre, Patrick, Basta, Tamara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814370/ https://www.ncbi.nlm.nih.gov/pubmed/23945934 http://dx.doi.org/10.1093/nar/gkt720

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