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Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis
Replication-dependent histones are encoded by multigene families found in several large clusters in the human genome and are thought to be functionally redundant. However, the abundance of specific replication-dependent isoforms of histone H2A is altered in patients with chronic lymphocytic leukemia...
Autores principales: | Singh, Rajbir, Mortazavi, Amir, Telu, Kelly H., Nagarajan, Prabakaran, Lucas, David M., Thomas-Ahner, Jennifer M., Clinton, Steven K., Byrd, John C., Freitas, Michael A., Parthun, Mark R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814372/ https://www.ncbi.nlm.nih.gov/pubmed/23956221 http://dx.doi.org/10.1093/nar/gkt736 |
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