Cargando…
Distinct isoforms of the Drosophila Brd4 homologue are present at enhancers, promoters and insulator sites
Brd4 is a double bromodomain protein that has been shown to interact with acetylated histones to regulate transcription by recruiting Positive Transcription Elongation Factor b to the promoter region. Brd4 is also involved in gene bookmarking during mitosis and is a therapeutic target for the treatm...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814382/ https://www.ncbi.nlm.nih.gov/pubmed/23945939 http://dx.doi.org/10.1093/nar/gkt722 |