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Distinct isoforms of the Drosophila Brd4 homologue are present at enhancers, promoters and insulator sites

Brd4 is a double bromodomain protein that has been shown to interact with acetylated histones to regulate transcription by recruiting Positive Transcription Elongation Factor b to the promoter region. Brd4 is also involved in gene bookmarking during mitosis and is a therapeutic target for the treatm...

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Detalles Bibliográficos
Autores principales:	Kellner, Wendy A., Van Bortle, Kevin, Li, Li, Ramos, Edward, Takenaka, Naomi, Corces, Victor G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814382/ https://www.ncbi.nlm.nih.gov/pubmed/23945939 http://dx.doi.org/10.1093/nar/gkt722

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