An age-related numerical and functional deficit in CD19(+)CD24(hi)CD38(hi) B cells is associated with an increase in systemic autoimmunity

Autoimmunity increases with aging indicative of reduced immune tolerance, but the mechanisms involved are poorly defined. In recent years, subsets of B cells with immunoregulatory properties have been identified in murine models of autoimmune disorders, and these cells downregulate immune responses...

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Detalles Bibliográficos
Autores principales: Duggal, Niharika A, Upton, Jane, Phillips, Anna C, Sapey, Elizabeth, Lord, Janet M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814412/
https://www.ncbi.nlm.nih.gov/pubmed/23755918
http://dx.doi.org/10.1111/acel.12114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814412/
https://www.ncbi.nlm.nih.gov/pubmed/23755918
http://dx.doi.org/10.1111/acel.12114

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