A Trypanosoma brucei Kinesin Heavy Chain Promotes Parasite Growth by Triggering Host Arginase Activity

BACKGROUND: In order to promote infection, the blood-borne parasite Trypanosoma brucei releases factors that upregulate arginase expression and activity in myeloid cells. METHODOLOGY/PRINCIPAL FINDINGS: By screening a cDNA library of T. brucei with an antibody neutralizing the arginase-inducing acti...

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Detalles Bibliográficos
Autores principales: De Muylder, Géraldine, Daulouède, Sylvie, Lecordier, Laurence, Uzureau, Pierrick, Morias, Yannick, Van Den Abbeele, Jan, Caljon, Guy, Hérin, Michel, Holzmuller, Philippe, Semballa, Silla, Courtois, Pierrette, Vanhamme, Luc, Stijlemans, Benoît, De Baetselier, Patrick, Barrett, Michael P., Barlow, Jillian L., McKenzie, Andrew N. J., Barron, Luke, Wynn, Thomas A., Beschin, Alain, Vincendeau, Philippe, Pays, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814429/
https://www.ncbi.nlm.nih.gov/pubmed/24204274
http://dx.doi.org/10.1371/journal.ppat.1003731

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