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Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus

Objective: Screening of complications is an important part of diabetes care. The aim of this study was to investigate diabetic complications and related risk factors in adolescents with type 1 diabetes mellitus (T1DM). Methods: This cross-sectional study was conducted on type 1 diabetics who were ov...

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Autores principales: Demirel, Fatma, Tepe, Derya, Kara, Özlem, Esen, İhsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814528/
https://www.ncbi.nlm.nih.gov/pubmed/24072081
http://dx.doi.org/10.4274/Jcrpe.994
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author Demirel, Fatma
Tepe, Derya
Kara, Özlem
Esen, İhsan
author_facet Demirel, Fatma
Tepe, Derya
Kara, Özlem
Esen, İhsan
author_sort Demirel, Fatma
collection PubMed
description Objective: Screening of complications is an important part of diabetes care. The aim of this study was to investigate diabetic complications and related risk factors in adolescents with type 1 diabetes mellitus (T1DM). Methods: This cross-sectional study was conducted on type 1 diabetics who were over 11 years of age or had a diabetes duration of 2 years and included 155 adolescents with T1DM (67 male, 88 female). The mean age of the patients was 14.4±2.1 years. Mean diabetes duration was 6.3±2.9 years. The patients were screened for diabetic nephropathy, retinopathy and peripheral neuropathy. Results: Mean glycosylated hemoglobin (HbA1c) level of the study group was 8.4%. The frequency of microalbuminuria and peripheral neuropathy were 16.1% and 0.6%, respectively. None of the patients had diabetic retinopathy. Dyslipidemia and hypertension rates were 30.3% and 12.3%, respectively. Risk factors associated with microalbuminuria were hypertension, higher HbA1c levels, longer diabetes duration and dyslipidemia. Conclusion: Early diagnosis and treatment of hypertension and dyslipidemia as well as achieving a better metabolic control are important in prevention or postponement of complications in patients with T1DM. Yearly screening for diabetic nephropathy should be started 2 years after the onset of the diabetes. Conflict of interest:None declared.
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spelling pubmed-38145282013-11-16 Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus Demirel, Fatma Tepe, Derya Kara, Özlem Esen, İhsan J Clin Res Pediatr Endocrinol Original Article Objective: Screening of complications is an important part of diabetes care. The aim of this study was to investigate diabetic complications and related risk factors in adolescents with type 1 diabetes mellitus (T1DM). Methods: This cross-sectional study was conducted on type 1 diabetics who were over 11 years of age or had a diabetes duration of 2 years and included 155 adolescents with T1DM (67 male, 88 female). The mean age of the patients was 14.4±2.1 years. Mean diabetes duration was 6.3±2.9 years. The patients were screened for diabetic nephropathy, retinopathy and peripheral neuropathy. Results: Mean glycosylated hemoglobin (HbA1c) level of the study group was 8.4%. The frequency of microalbuminuria and peripheral neuropathy were 16.1% and 0.6%, respectively. None of the patients had diabetic retinopathy. Dyslipidemia and hypertension rates were 30.3% and 12.3%, respectively. Risk factors associated with microalbuminuria were hypertension, higher HbA1c levels, longer diabetes duration and dyslipidemia. Conclusion: Early diagnosis and treatment of hypertension and dyslipidemia as well as achieving a better metabolic control are important in prevention or postponement of complications in patients with T1DM. Yearly screening for diabetic nephropathy should be started 2 years after the onset of the diabetes. Conflict of interest:None declared. Galenos Publishing 2013-09 2013-09-18 /pmc/articles/PMC3814528/ /pubmed/24072081 http://dx.doi.org/10.4274/Jcrpe.994 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Demirel, Fatma
Tepe, Derya
Kara, Özlem
Esen, İhsan
Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
title Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
title_full Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
title_fullStr Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
title_full_unstemmed Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
title_short Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
title_sort microvascular complications in adolescents with type 1 diabetes mellitus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814528/
https://www.ncbi.nlm.nih.gov/pubmed/24072081
http://dx.doi.org/10.4274/Jcrpe.994
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