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Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus
Objective: Screening of complications is an important part of diabetes care. The aim of this study was to investigate diabetic complications and related risk factors in adolescents with type 1 diabetes mellitus (T1DM). Methods: This cross-sectional study was conducted on type 1 diabetics who were ov...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814528/ https://www.ncbi.nlm.nih.gov/pubmed/24072081 http://dx.doi.org/10.4274/Jcrpe.994 |
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author | Demirel, Fatma Tepe, Derya Kara, Özlem Esen, İhsan |
author_facet | Demirel, Fatma Tepe, Derya Kara, Özlem Esen, İhsan |
author_sort | Demirel, Fatma |
collection | PubMed |
description | Objective: Screening of complications is an important part of diabetes care. The aim of this study was to investigate diabetic complications and related risk factors in adolescents with type 1 diabetes mellitus (T1DM). Methods: This cross-sectional study was conducted on type 1 diabetics who were over 11 years of age or had a diabetes duration of 2 years and included 155 adolescents with T1DM (67 male, 88 female). The mean age of the patients was 14.4±2.1 years. Mean diabetes duration was 6.3±2.9 years. The patients were screened for diabetic nephropathy, retinopathy and peripheral neuropathy. Results: Mean glycosylated hemoglobin (HbA1c) level of the study group was 8.4%. The frequency of microalbuminuria and peripheral neuropathy were 16.1% and 0.6%, respectively. None of the patients had diabetic retinopathy. Dyslipidemia and hypertension rates were 30.3% and 12.3%, respectively. Risk factors associated with microalbuminuria were hypertension, higher HbA1c levels, longer diabetes duration and dyslipidemia. Conclusion: Early diagnosis and treatment of hypertension and dyslipidemia as well as achieving a better metabolic control are important in prevention or postponement of complications in patients with T1DM. Yearly screening for diabetic nephropathy should be started 2 years after the onset of the diabetes. Conflict of interest:None declared. |
format | Online Article Text |
id | pubmed-3814528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-38145282013-11-16 Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus Demirel, Fatma Tepe, Derya Kara, Özlem Esen, İhsan J Clin Res Pediatr Endocrinol Original Article Objective: Screening of complications is an important part of diabetes care. The aim of this study was to investigate diabetic complications and related risk factors in adolescents with type 1 diabetes mellitus (T1DM). Methods: This cross-sectional study was conducted on type 1 diabetics who were over 11 years of age or had a diabetes duration of 2 years and included 155 adolescents with T1DM (67 male, 88 female). The mean age of the patients was 14.4±2.1 years. Mean diabetes duration was 6.3±2.9 years. The patients were screened for diabetic nephropathy, retinopathy and peripheral neuropathy. Results: Mean glycosylated hemoglobin (HbA1c) level of the study group was 8.4%. The frequency of microalbuminuria and peripheral neuropathy were 16.1% and 0.6%, respectively. None of the patients had diabetic retinopathy. Dyslipidemia and hypertension rates were 30.3% and 12.3%, respectively. Risk factors associated with microalbuminuria were hypertension, higher HbA1c levels, longer diabetes duration and dyslipidemia. Conclusion: Early diagnosis and treatment of hypertension and dyslipidemia as well as achieving a better metabolic control are important in prevention or postponement of complications in patients with T1DM. Yearly screening for diabetic nephropathy should be started 2 years after the onset of the diabetes. Conflict of interest:None declared. Galenos Publishing 2013-09 2013-09-18 /pmc/articles/PMC3814528/ /pubmed/24072081 http://dx.doi.org/10.4274/Jcrpe.994 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Demirel, Fatma Tepe, Derya Kara, Özlem Esen, İhsan Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus |
title | Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus |
title_full | Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus |
title_fullStr | Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus |
title_full_unstemmed | Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus |
title_short | Microvascular Complications in Adolescents with Type 1 Diabetes Mellitus |
title_sort | microvascular complications in adolescents with type 1 diabetes mellitus |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814528/ https://www.ncbi.nlm.nih.gov/pubmed/24072081 http://dx.doi.org/10.4274/Jcrpe.994 |
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