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Medical Management of Thyroid Ectopia: Report of Three Cases

Thyroid ectopia (TE) is an embryological aberration of the thyroid gland migration most commonly observed in the lingual region followed by the sublingual, hyoid, and mediastinal regions. TE is often complicated by local compressive symptoms resulting in dysphagia, dysphonia, and dyspnea. Surgical r...

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Autores principales: Dutta, Deep, Kumar, Manoj, Thukral, Anubhav, Biswas, Dibakar, Jain, Rajesh, Ghosh, Sujoy, Mukhopadhyay, Satinath, Chowdhury, Subhankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814540/
https://www.ncbi.nlm.nih.gov/pubmed/24072094
http://dx.doi.org/10.4274/Jcrpe.1103
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author Dutta, Deep
Kumar, Manoj
Thukral, Anubhav
Biswas, Dibakar
Jain, Rajesh
Ghosh, Sujoy
Mukhopadhyay, Satinath
Chowdhury, Subhankar
author_facet Dutta, Deep
Kumar, Manoj
Thukral, Anubhav
Biswas, Dibakar
Jain, Rajesh
Ghosh, Sujoy
Mukhopadhyay, Satinath
Chowdhury, Subhankar
author_sort Dutta, Deep
collection PubMed
description Thyroid ectopia (TE) is an embryological aberration of the thyroid gland migration most commonly observed in the lingual region followed by the sublingual, hyoid, and mediastinal regions. TE is often complicated by local compressive symptoms resulting in dysphagia, dysphonia, and dyspnea. Surgical removal of TE is frequently complicated by difficulties in intubation, increased perioperative bleeding, and severe primary hypothyroidism; on the other hand, I131 ablation is limited by high doses needed and the concern for long-term effects especially in children. We report three children with TE who all presented with compressive symptoms and were managed conservatively with levothyroxine resulting in resolution of compressive symptoms and favorable outcomes. Levothyroxine supplementation is effective and has an important role in managing TE, not only in correcting the associated hypothyroidism but also in resolving the associated compressive symptoms by reducing the size of the ectopic thyroid tissue. Conflict of interest:None declared.
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spelling pubmed-38145402013-11-16 Medical Management of Thyroid Ectopia: Report of Three Cases Dutta, Deep Kumar, Manoj Thukral, Anubhav Biswas, Dibakar Jain, Rajesh Ghosh, Sujoy Mukhopadhyay, Satinath Chowdhury, Subhankar J Clin Res Pediatr Endocrinol Case Report Thyroid ectopia (TE) is an embryological aberration of the thyroid gland migration most commonly observed in the lingual region followed by the sublingual, hyoid, and mediastinal regions. TE is often complicated by local compressive symptoms resulting in dysphagia, dysphonia, and dyspnea. Surgical removal of TE is frequently complicated by difficulties in intubation, increased perioperative bleeding, and severe primary hypothyroidism; on the other hand, I131 ablation is limited by high doses needed and the concern for long-term effects especially in children. We report three children with TE who all presented with compressive symptoms and were managed conservatively with levothyroxine resulting in resolution of compressive symptoms and favorable outcomes. Levothyroxine supplementation is effective and has an important role in managing TE, not only in correcting the associated hypothyroidism but also in resolving the associated compressive symptoms by reducing the size of the ectopic thyroid tissue. Conflict of interest:None declared. Galenos Publishing 2013-09 2013-09-18 /pmc/articles/PMC3814540/ /pubmed/24072094 http://dx.doi.org/10.4274/Jcrpe.1103 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dutta, Deep
Kumar, Manoj
Thukral, Anubhav
Biswas, Dibakar
Jain, Rajesh
Ghosh, Sujoy
Mukhopadhyay, Satinath
Chowdhury, Subhankar
Medical Management of Thyroid Ectopia: Report of Three Cases
title Medical Management of Thyroid Ectopia: Report of Three Cases
title_full Medical Management of Thyroid Ectopia: Report of Three Cases
title_fullStr Medical Management of Thyroid Ectopia: Report of Three Cases
title_full_unstemmed Medical Management of Thyroid Ectopia: Report of Three Cases
title_short Medical Management of Thyroid Ectopia: Report of Three Cases
title_sort medical management of thyroid ectopia: report of three cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814540/
https://www.ncbi.nlm.nih.gov/pubmed/24072094
http://dx.doi.org/10.4274/Jcrpe.1103
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