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West Nile Virus Antibody Prevalence in Horses in Ukraine

West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years...

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Autores principales: Ziegler, Ute, Skrypnyk, Artem, Keller, Markus, Staubach, Christoph, Bezymennyi, Maksym, Damiani, Armando M., Osterrieder, Nikolaus, Groschup, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814598/
https://www.ncbi.nlm.nih.gov/pubmed/24100889
http://dx.doi.org/10.3390/v5102469
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author Ziegler, Ute
Skrypnyk, Artem
Keller, Markus
Staubach, Christoph
Bezymennyi, Maksym
Damiani, Armando M.
Osterrieder, Nikolaus
Groschup, Martin H.
author_facet Ziegler, Ute
Skrypnyk, Artem
Keller, Markus
Staubach, Christoph
Bezymennyi, Maksym
Damiani, Armando M.
Osterrieder, Nikolaus
Groschup, Martin H.
author_sort Ziegler, Ute
collection PubMed
description West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country.
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spelling pubmed-38145982013-11-01 West Nile Virus Antibody Prevalence in Horses in Ukraine Ziegler, Ute Skrypnyk, Artem Keller, Markus Staubach, Christoph Bezymennyi, Maksym Damiani, Armando M. Osterrieder, Nikolaus Groschup, Martin H. Viruses Article West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country. MDPI 2013-10-04 /pmc/articles/PMC3814598/ /pubmed/24100889 http://dx.doi.org/10.3390/v5102469 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Ziegler, Ute
Skrypnyk, Artem
Keller, Markus
Staubach, Christoph
Bezymennyi, Maksym
Damiani, Armando M.
Osterrieder, Nikolaus
Groschup, Martin H.
West Nile Virus Antibody Prevalence in Horses in Ukraine
title West Nile Virus Antibody Prevalence in Horses in Ukraine
title_full West Nile Virus Antibody Prevalence in Horses in Ukraine
title_fullStr West Nile Virus Antibody Prevalence in Horses in Ukraine
title_full_unstemmed West Nile Virus Antibody Prevalence in Horses in Ukraine
title_short West Nile Virus Antibody Prevalence in Horses in Ukraine
title_sort west nile virus antibody prevalence in horses in ukraine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814598/
https://www.ncbi.nlm.nih.gov/pubmed/24100889
http://dx.doi.org/10.3390/v5102469
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