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West Nile Virus Antibody Prevalence in Horses in Ukraine
West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814598/ https://www.ncbi.nlm.nih.gov/pubmed/24100889 http://dx.doi.org/10.3390/v5102469 |
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author | Ziegler, Ute Skrypnyk, Artem Keller, Markus Staubach, Christoph Bezymennyi, Maksym Damiani, Armando M. Osterrieder, Nikolaus Groschup, Martin H. |
author_facet | Ziegler, Ute Skrypnyk, Artem Keller, Markus Staubach, Christoph Bezymennyi, Maksym Damiani, Armando M. Osterrieder, Nikolaus Groschup, Martin H. |
author_sort | Ziegler, Ute |
collection | PubMed |
description | West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country. |
format | Online Article Text |
id | pubmed-3814598 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-38145982013-11-01 West Nile Virus Antibody Prevalence in Horses in Ukraine Ziegler, Ute Skrypnyk, Artem Keller, Markus Staubach, Christoph Bezymennyi, Maksym Damiani, Armando M. Osterrieder, Nikolaus Groschup, Martin H. Viruses Article West Nile virus (WNV) is a mosquito-borne virus of global importance. Over the last two decades, it has been responsible for significant numbers of cases of illness in humans and animals in many parts of the world. In Ukraine, WNV infections in humans and birds were first reported more than 25 years ago, yet the current epidemiological status is quite unclear. In this study, serum samples from over 300 equines were collected and screened in order to detect current WNV activity in Ukraine with the goal to estimate the risk of infection for humans and horses. Sera were tested by enzyme-linked immunosorbent assay (ELISA) and virus neutralization assay (NT) to detect WNV-specific antibodies. The results clearly revealed that WNV circulates in most of the regions from which samples were obtained, shown by a WNV seroprevalence rate of 13.5% of examined horses. This is the first topical report indicating the presence of WNV infections in horses in Ukraine, and the results of this study provide evidence of a widespread WNV circulation in this country. MDPI 2013-10-04 /pmc/articles/PMC3814598/ /pubmed/24100889 http://dx.doi.org/10.3390/v5102469 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Ziegler, Ute Skrypnyk, Artem Keller, Markus Staubach, Christoph Bezymennyi, Maksym Damiani, Armando M. Osterrieder, Nikolaus Groschup, Martin H. West Nile Virus Antibody Prevalence in Horses in Ukraine |
title | West Nile Virus Antibody Prevalence in Horses in Ukraine |
title_full | West Nile Virus Antibody Prevalence in Horses in Ukraine |
title_fullStr | West Nile Virus Antibody Prevalence in Horses in Ukraine |
title_full_unstemmed | West Nile Virus Antibody Prevalence in Horses in Ukraine |
title_short | West Nile Virus Antibody Prevalence in Horses in Ukraine |
title_sort | west nile virus antibody prevalence in horses in ukraine |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814598/ https://www.ncbi.nlm.nih.gov/pubmed/24100889 http://dx.doi.org/10.3390/v5102469 |
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