Identification of Strain-Specific B-cell Epitopes in Trypanosoma cruzi Using Genome-Scale Epitope Prediction and High-Throughput Immunoscreening with Peptide Arrays

BACKGROUND: The factors influencing variation in the clinical forms of Chagas disease have not been elucidated; however, it is likely that the genetics of both the host and the parasite are involved. Several studies have attempted to correlate the T. cruzi strains involved in infection with the clin...

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Detalles Bibliográficos
Autores principales: Mendes, Tiago Antônio de Oliveira, Reis Cunha, João Luís, de Almeida Lourdes, Rodrigo, Rodrigues Luiz, Gabriela Flávia, Lemos, Lucas Dhom, dos Santos, Ana Rita Rocha, da Câmara, Antônia Cláudia Jácome, Galvão, Lúcia Maria da Cunha, Bern, Caryn, Gilman, Robert H., Fujiwara, Ricardo Toshio, Gazzinelli, Ricardo Tostes, Bartholomeu, Daniella Castanheira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814679/
https://www.ncbi.nlm.nih.gov/pubmed/24205430
http://dx.doi.org/10.1371/journal.pntd.0002524

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