SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress

ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1, formerly PARP1) is localized in the nucleus, where it ADP-ribosylates specific target proteins. The post-translational modification (PTM) with a single ADP-ribose unit or with polymeric ADP-ribose (PAR) chains regulates protein function as well...

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Detalles Bibliográficos
Autores principales: Kassner, Ingrid, Andersson, Anneli, Fey, Monika, Tomas, Martin, Ferrando-May, Elisa, Hottiger, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814718/
https://www.ncbi.nlm.nih.gov/pubmed/24088713
http://dx.doi.org/10.1098/rsob.120173

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