Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression

Autosomal recessive primary microcephaly (MCPH) is a congenital disorder characterized by significantly reduced brain size and mental retardation. Nine genes are currently known to be associated with the condition, all of which encode centrosomal or spindle pole proteins. MCPH is associated with a r...

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Detalles Bibliográficos
Autores principales: Novorol, Claire, Burkhardt, Janina, Wood, Kirstin J., Iqbal, Anila, Roque, Claudio, Coutts, Nicola, Almeida, Alexandra D., He, Jie, Wilkinson, Christopher J., Harris, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814721/
https://www.ncbi.nlm.nih.gov/pubmed/24153002
http://dx.doi.org/10.1098/rsob.130065

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