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Mitochondrial DNA Subhaplogroups L0a2 and L2a Modify Susceptibility to Peripheral Neuropathy in Malawian Adults on Stavudine Containing Highly Active Antiretroviral Therapy

BACKGROUND: Peripheral neuropathy (PN) is one of the main toxicities associated with stavudine. Genetic variants in mitochondrial DNA (mtDNA) haplogroups have been associated with increased risk of developing PN in European non-Hispanic and black patients on stavudine containing antiretroviral thera...

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Detalles Bibliográficos
Autores principales:	Kampira, Elizabeth, Kumwenda, Johnstone, van Oosterhout, Joep J., Dandara, Collet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JAIDS Journal of Acquired Immune Deficiency Syndromes 2013
Materias:	Epidemiology and Prevention
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815091/ https://www.ncbi.nlm.nih.gov/pubmed/23614993 http://dx.doi.org/10.1097/QAI.0b013e3182968ea5

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