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APP Regulates NGF Receptor Trafficking and NGF-Mediated Neuronal Differentiation and Survival
β-amyloid precursor protein (APP) is a key factor in Alzheimer's disease (AD) but its physiological function is largely undetermined. APP has been found to regulate retrograde transport of nerve growth factor (NGF), which plays a crucial role in mediating neuronal survival and differentiation....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815101/ https://www.ncbi.nlm.nih.gov/pubmed/24224055 http://dx.doi.org/10.1371/journal.pone.0080571 |