New Insights into the RNA-Based Mechanism of Action of the Anticancer Drug 5′-Fluorouracil in Eukaryotic Cells

5-Fluorouracil (5FU) is a chemotherapeutic drug widely used in treating a range of advanced, solid tumours and, in particular, colorectal cancer. Here, we used high-density tiling DNA microarray technology to obtain the specific transcriptome-wide response induced by 5FU in the eukaryotic model Schi...

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Detalles Bibliográficos
Autores principales: Mojardín, Laura, Botet, Javier, Quintales, Luis, Moreno, Sergio, Salas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815194/
https://www.ncbi.nlm.nih.gov/pubmed/24223771
http://dx.doi.org/10.1371/journal.pone.0078172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815194/
https://www.ncbi.nlm.nih.gov/pubmed/24223771
http://dx.doi.org/10.1371/journal.pone.0078172

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