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New Insights into the RNA-Based Mechanism of Action of the Anticancer Drug 5′-Fluorouracil in Eukaryotic Cells

5-Fluorouracil (5FU) is a chemotherapeutic drug widely used in treating a range of advanced, solid tumours and, in particular, colorectal cancer. Here, we used high-density tiling DNA microarray technology to obtain the specific transcriptome-wide response induced by 5FU in the eukaryotic model Schi...

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Detalles Bibliográficos
Autores principales:	Mojardín, Laura, Botet, Javier, Quintales, Luis, Moreno, Sergio, Salas, Margarita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815194/ https://www.ncbi.nlm.nih.gov/pubmed/24223771 http://dx.doi.org/10.1371/journal.pone.0078172

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