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Modeling the Dynamics of Bivalent Histone Modifications

Epigenetic modifications to histones may promote either activation or repression of the transcription of nearby genes. Recent experimental studies show that the promoters of many lineage-control genes in stem cells have “bivalent domains” in which the nucleosomes contain both active (H3K4me3) and re...

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Detalles Bibliográficos
Autores principales: Ku, Wai Lim, Girvan, Michelle, Yuan, Guo-Cheng, Sorrentino, Francesco, Ott, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815350/
https://www.ncbi.nlm.nih.gov/pubmed/24223747
http://dx.doi.org/10.1371/journal.pone.0077944

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