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Uracil influences quorum sensing and biofilm formation in Pseudomonas aeruginosa and fluorouracil is an antagonist

Pseudomonas aeruginosa is an ubiquitous, opportunistic pathogen whose biofilms are notoriously difficult to control. Here we discover uracil influences all three known quorum‐sensing (QS) pathways of P. aeruginosa. By screening 5850 transposon mutants for altered biofilm formation, we identified sev...

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Detalles Bibliográficos
Autores principales: Ueda, Akihiro, Attila, Can, Whiteley, Marvin, Wood, Thomas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815422/
https://www.ncbi.nlm.nih.gov/pubmed/21261882
http://dx.doi.org/10.1111/j.1751-7915.2008.00060.x

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