Recombinant DNA production of spider silk proteins

Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein-based materials. Recent advances in genetic engineering make it possible to produce recombinant silks...

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Detalles Bibliográficos
Autores principales: Tokareva, Olena, Michalczechen-Lacerda, Valquíria A, Rech, Elíbio L, Kaplan, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815454/
https://www.ncbi.nlm.nih.gov/pubmed/24119078
http://dx.doi.org/10.1111/1751-7915.12081
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author Tokareva, Olena
Michalczechen-Lacerda, Valquíria A
Rech, Elíbio L
Kaplan, David L
author_facet Tokareva, Olena
Michalczechen-Lacerda, Valquíria A
Rech, Elíbio L
Kaplan, David L
author_sort Tokareva, Olena
collection PubMed
description Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein-based materials. Recent advances in genetic engineering make it possible to produce recombinant silks in heterologous hosts, opening up opportunities for large-scale production of recombinant silks for various biomedical and material science applications. We review the current strategies to produce recombinant spider silks.
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spelling pubmed-38154542014-02-12 Recombinant DNA production of spider silk proteins Tokareva, Olena Michalczechen-Lacerda, Valquíria A Rech, Elíbio L Kaplan, David L Microb Biotechnol Minireviews Spider dragline silk is considered to be the toughest biopolymer on Earth due to an extraordinary combination of strength and elasticity. Moreover, silks are biocompatible and biodegradable protein-based materials. Recent advances in genetic engineering make it possible to produce recombinant silks in heterologous hosts, opening up opportunities for large-scale production of recombinant silks for various biomedical and material science applications. We review the current strategies to produce recombinant spider silks. Blackwell Publishing Ltd 2013-11 2013-10-11 /pmc/articles/PMC3815454/ /pubmed/24119078 http://dx.doi.org/10.1111/1751-7915.12081 Text en Journal compilation © 2013 John Wiley & Sons Ltd and Society for Applied Microbiology http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
spellingShingle Minireviews
Tokareva, Olena
Michalczechen-Lacerda, Valquíria A
Rech, Elíbio L
Kaplan, David L
Recombinant DNA production of spider silk proteins
title Recombinant DNA production of spider silk proteins
title_full Recombinant DNA production of spider silk proteins
title_fullStr Recombinant DNA production of spider silk proteins
title_full_unstemmed Recombinant DNA production of spider silk proteins
title_short Recombinant DNA production of spider silk proteins
title_sort recombinant dna production of spider silk proteins
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815454/
https://www.ncbi.nlm.nih.gov/pubmed/24119078
http://dx.doi.org/10.1111/1751-7915.12081
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