FUNCTIONAL EVALUATION OF AUTISM-ASSOCIATED MUTATIONS IN NHE9

NHE9 (SLC9A9) is an endosomal cation/proton antiporter with orthologs in yeast and bacteria. Rare, missense substitutions in NHE9 are genetically linked with autism, but have not been functionally evaluated. Here we use evolutionary conservation analysis to build a model-structure of NHE9 based on t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kondapalli, Kalyan C., Hack, Anniesha, Schushan, Maya, Landau, Meytal, Ben-Tal, Nir, Rao, Rajini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815575/
https://www.ncbi.nlm.nih.gov/pubmed/24065030
http://dx.doi.org/10.1038/ncomms3510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815575/
https://www.ncbi.nlm.nih.gov/pubmed/24065030
http://dx.doi.org/10.1038/ncomms3510

Ejemplares similares