Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving

In rat models of drug relapse and craving, cue-induced cocaine seeking progressively increases after drug withdrawal. This ‘incubation of cocaine craving’ is partially mediated by time-dependent adaptations at glutamatergic synapses in nucleus accumbens. However, the circuit-level adaptations mediat...

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Detalles Bibliográficos
Autores principales: Lee, Brian R., Ma, Yao-ying, Huang, Yanhua H., Wang, Xiusong, Otaka, Mami, Ishikawa, Masago, Neumann, Peter A., Graziane, Nicolas M., Brown, Travis E., Suska, Anna, Guo, Changyong, Lobo, Mary Kay, Sesack, Susan R., Wolf, Marina E., Nestler, Eric J., Shaham, Yavin, Schlüter, Oliver M., Dong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815713/
https://www.ncbi.nlm.nih.gov/pubmed/24077564
http://dx.doi.org/10.1038/nn.3533

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