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Synthesis of ω-hydroxy dodecanoic acid based on an engineered CYP153A fusion construct

A bacterial P450 monooxygenase-based whole cell biocatalyst using Escherichia coli has been applied in the production of ω-hydroxy dodecanoic acid from dodecanoic acid (C12-FA) or the corresponding methyl ester. We have constructed and purified a chimeric protein where the fusion of the monooxygenas...

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Detalles Bibliográficos
Autores principales:	Scheps, Daniel, Honda Malca, Sumire, Richter, Sven M, Marisch, Karoline, Nestl, Bettina M, Hauer, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815936/ https://www.ncbi.nlm.nih.gov/pubmed/23941649 http://dx.doi.org/10.1111/1751-7915.12073

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