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An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression
The establishment and maintenance of central tolerance depends to a large extent on the ability of medullary thymic epithelial cells to express a variety of tissue-restricted antigens, the so-called promiscuous gene expression (pGE). Autoimmune regulator (Aire) is to date the best characterised tran...
Autores principales: | Ucar, Olga, Tykocinski, Lars-Oliver, Dooley, James, Liston, Adrian, Kyewski, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816332/ https://www.ncbi.nlm.nih.gov/pubmed/23589212 http://dx.doi.org/10.1002/eji.201343343 |
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