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Iterative Correction of Hi-C Data Reveals Hallmarks of Chromosome Organization

Extracting biologically meaningful information from chromosomal interactions obtained with genome-wide chromosome conformation capture (3C) analyses requires elimination of systematic biases. We present a pipeline that integrates a strategy for mapping of sequencing reads and a data-driven method fo...

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Detalles Bibliográficos
Autores principales:	Imakaev, Maxim, Fudenberg, Geoffrey, McCord, Rachel Patton, Naumova, Natalia, Goloborodko, Anton, Lajoie, Bryan R., Dekker, Job, Mirny, Leonid A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816492/ https://www.ncbi.nlm.nih.gov/pubmed/22941365 http://dx.doi.org/10.1038/nmeth.2148

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