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Epigenetic drug 5-azacytidine impairs proliferation of rat limb buds in an organotypic model-system in vitro
AIM: To establish an organotypic in vitro model of limb bud development to verify whether epigenetic drug and teratogen 5-azacytidine (5azaC) has an effect on limb buds independent of its effects on the placenta. METHODS: Fischer strain rat fore- and hindlimb buds were microsurgically isolated from...
Autores principales: | Mužić, Vedrana, Katušić Bojanac, Ana, Jurić-Lekić, Gordana, Himelreich, Marta, Tupek, Katarina, Šerman, Ljiljana, Marn, Nina, Sinčić, Nino, Vlahović, Maja, Bulić-Jakuš, Floriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Croatian Medical Schools
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816559/ https://www.ncbi.nlm.nih.gov/pubmed/24170728 http://dx.doi.org/10.3325/cmj.2013.54.489 |
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