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Periodontal conditions in patients with Marfan syndrome – a multicenter case control study
BACKGROUND: Marfan syndrome (MFS) is a disorder of the connective tissues. Alterations of the elastic fibers may manifest in different tissues especially in the skeletal, cardiovascular and ocular system. Oral manifestations like orthodontic or skeletal anomalies and fragility of the temporomandibul...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816571/ https://www.ncbi.nlm.nih.gov/pubmed/24165013 http://dx.doi.org/10.1186/1472-6831-13-59 |
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author | Staufenbiel, Ingmar Hauschild, Christian Kahl-Nieke, Bärbel Vahle-Hinz, Eva von Kodolitsch, Yskert Berner, Maike Bauss, Oskar Geurtsen, Werner Rahman, Alexander |
author_facet | Staufenbiel, Ingmar Hauschild, Christian Kahl-Nieke, Bärbel Vahle-Hinz, Eva von Kodolitsch, Yskert Berner, Maike Bauss, Oskar Geurtsen, Werner Rahman, Alexander |
author_sort | Staufenbiel, Ingmar |
collection | PubMed |
description | BACKGROUND: Marfan syndrome (MFS) is a disorder of the connective tissues. Alterations of the elastic fibers may manifest in different tissues especially in the skeletal, cardiovascular and ocular system. Oral manifestations like orthodontic or skeletal anomalies and fragility of the temporomandibular joint have been well described by various authors. However, no data are available regarding a possible periodontal involvement of MFS. Hence, the aim of the present study was to investigate for the first time if MFS may increase the susceptibility to periodontitis. METHODS: A comprehensive periodontal examination including documentation of probing pocket depth, gingival recession, clinical attachment level, and bleeding on probing was conducted in all patients. In addition, dental conditions were assessed by determining the Index for Decayed, Missing and Filled Teeth (DMFT) and a self-administered questionnaire was filled out by patients. For statistical analysis, the unpaired t-Test was applied (level of significance: p < 0.05). Both groups were matched concerning well known periodontal risk factors like age, gender and smoking habits. RESULTS: 82 participants, 51 patients with MFS (30 female and 21 male, mean age: 40.20 ± 15.35 years) and 31 sound controls (17 female and 14 male, mean age: 40.29 ± 13.94 years), were examined. All assessed periodontal and dental parameters were not significantly different between groups. CONCLUSIONS: Based on our data, patients with MFS did not reveal a higher prevalence of periodontitis compared to the control group. However, Marfan patients showed a tendency to more inflammation signs, which can be explained by the crowded teeth. Therefore, a regular professional cleaning of the teeth is recommendable (i.e., 6 months intervals) in order to reduce the bacterial biofilm in the oral cavity and thus resulting in a decreased risk of systemic diseases, specifically endocarditis. |
format | Online Article Text |
id | pubmed-3816571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-38165712013-11-05 Periodontal conditions in patients with Marfan syndrome – a multicenter case control study Staufenbiel, Ingmar Hauschild, Christian Kahl-Nieke, Bärbel Vahle-Hinz, Eva von Kodolitsch, Yskert Berner, Maike Bauss, Oskar Geurtsen, Werner Rahman, Alexander BMC Oral Health Research Article BACKGROUND: Marfan syndrome (MFS) is a disorder of the connective tissues. Alterations of the elastic fibers may manifest in different tissues especially in the skeletal, cardiovascular and ocular system. Oral manifestations like orthodontic or skeletal anomalies and fragility of the temporomandibular joint have been well described by various authors. However, no data are available regarding a possible periodontal involvement of MFS. Hence, the aim of the present study was to investigate for the first time if MFS may increase the susceptibility to periodontitis. METHODS: A comprehensive periodontal examination including documentation of probing pocket depth, gingival recession, clinical attachment level, and bleeding on probing was conducted in all patients. In addition, dental conditions were assessed by determining the Index for Decayed, Missing and Filled Teeth (DMFT) and a self-administered questionnaire was filled out by patients. For statistical analysis, the unpaired t-Test was applied (level of significance: p < 0.05). Both groups were matched concerning well known periodontal risk factors like age, gender and smoking habits. RESULTS: 82 participants, 51 patients with MFS (30 female and 21 male, mean age: 40.20 ± 15.35 years) and 31 sound controls (17 female and 14 male, mean age: 40.29 ± 13.94 years), were examined. All assessed periodontal and dental parameters were not significantly different between groups. CONCLUSIONS: Based on our data, patients with MFS did not reveal a higher prevalence of periodontitis compared to the control group. However, Marfan patients showed a tendency to more inflammation signs, which can be explained by the crowded teeth. Therefore, a regular professional cleaning of the teeth is recommendable (i.e., 6 months intervals) in order to reduce the bacterial biofilm in the oral cavity and thus resulting in a decreased risk of systemic diseases, specifically endocarditis. BioMed Central 2013-10-28 /pmc/articles/PMC3816571/ /pubmed/24165013 http://dx.doi.org/10.1186/1472-6831-13-59 Text en Copyright © 2013 Staufenbiel et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Staufenbiel, Ingmar Hauschild, Christian Kahl-Nieke, Bärbel Vahle-Hinz, Eva von Kodolitsch, Yskert Berner, Maike Bauss, Oskar Geurtsen, Werner Rahman, Alexander Periodontal conditions in patients with Marfan syndrome – a multicenter case control study |
title | Periodontal conditions in patients with Marfan syndrome – a multicenter case control study |
title_full | Periodontal conditions in patients with Marfan syndrome – a multicenter case control study |
title_fullStr | Periodontal conditions in patients with Marfan syndrome – a multicenter case control study |
title_full_unstemmed | Periodontal conditions in patients with Marfan syndrome – a multicenter case control study |
title_short | Periodontal conditions in patients with Marfan syndrome – a multicenter case control study |
title_sort | periodontal conditions in patients with marfan syndrome – a multicenter case control study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816571/ https://www.ncbi.nlm.nih.gov/pubmed/24165013 http://dx.doi.org/10.1186/1472-6831-13-59 |
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