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In vitro study of combined cilengitide and radiation treatment in breast cancer cell lines

BACKGROUND: Brain metastasis from breast cancer poses a major clinical challenge. Integrins play a role in regulating adhesion, growth, motility, and survival, and have been shown to be critical for metastatic growth in the brain in preclinical models. Cilengitide, an αvβ3/αvβ5 integrin inhibitor, h...

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Detalles Bibliográficos
Autores principales:	Lautenschlaeger, Tim, Perry, James, Peereboom, David, Li, Bin, Ibrahim, Ahmed, Huebner, Alexander, Meng, Wei, White, Julia, Chakravarti, Arnab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816586/ https://www.ncbi.nlm.nih.gov/pubmed/24153102 http://dx.doi.org/10.1186/1748-717X-8-246

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