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Thiopurine methyltransferase genotyping in Palestinian childhood acute lymphoblastic leukemia patients

BACKGROUND: The genetic polymorphism of thiopurine methyltransferase (TPMT) is well characterized in most populations. Four common polymorphic alleles are associated with impaired activity of the enzyme. These are TPMT*2 (238G>C), TPMT*3B (c.460G>A), TPMT*3A (c.460G>A and c.719A>G) and T...

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Detalles Bibliográficos
Autores principales:	Ayesh, Basim Mohammad, Harb, Wael Mohammad, Abed, Abdalla Assaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816621/ https://www.ncbi.nlm.nih.gov/pubmed/24499706 http://dx.doi.org/10.1186/2052-1839-13-3

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