N-/O-glycosylation analysis of human FVIIa produced in the milk of transgenic rabbits

Human coagulation factor VIIa is a glycoprotein that promotes haemostasis through activation of the coagulation cascade extrinsic pathway. Most haemophilia A/B patients with inhibitors are treated by injection of plasma-derived or recombinant FVIIa. The use of recombinant products raises questions a...

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Detalles Bibliográficos
Autores principales: Chevreux, Guillaume, Faid, Valegh, Scohyers, Jean-Marc, Bihoreau, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816631/
https://www.ncbi.nlm.nih.gov/pubmed/24092837
http://dx.doi.org/10.1093/glycob/cwt085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816631/
https://www.ncbi.nlm.nih.gov/pubmed/24092837
http://dx.doi.org/10.1093/glycob/cwt085

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