Norethindrone Acetate in the Medical Management of Adenomyosis

The role of norethindrone acetate (NA) in the management of adenomyosis was evaluated with a retrospective chart review of 28 premenopausal women between 27–49 years of age presenting with moderate to severe pelvic pain and bleeding. Bleeding and dysmenorrhea scores were analyzed using paired T-test...

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Autores principales: Muneyyirci-Delale, Ozgul, Chandrareddy, Ashadeep, Mankame, Siddhi, Osei-Tutu, Nanna, von Gizycki, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816659/
https://www.ncbi.nlm.nih.gov/pubmed/24281260
http://dx.doi.org/10.3390/ph5101120
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author Muneyyirci-Delale, Ozgul
Chandrareddy, Ashadeep
Mankame, Siddhi
Osei-Tutu, Nanna
von Gizycki, Hans
author_facet Muneyyirci-Delale, Ozgul
Chandrareddy, Ashadeep
Mankame, Siddhi
Osei-Tutu, Nanna
von Gizycki, Hans
author_sort Muneyyirci-Delale, Ozgul
collection PubMed
description The role of norethindrone acetate (NA) in the management of adenomyosis was evaluated with a retrospective chart review of 28 premenopausal women between 27–49 years of age presenting with moderate to severe pelvic pain and bleeding. Bleeding and dysmenorrhea scores were analyzed using paired T-tests. There was significant improvement of both dysmenorrhea and bleeding after treatment. Age showed no correlation with dysmenorrhea or bleeding. Low dose NA could be considered an effective, well-tolerated and inexpensive medical alternative to surgery for treating symptomatic adenomyosis. Large multicentric studies may help validate our findings.
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spelling pubmed-38166592013-11-14 Norethindrone Acetate in the Medical Management of Adenomyosis Muneyyirci-Delale, Ozgul Chandrareddy, Ashadeep Mankame, Siddhi Osei-Tutu, Nanna von Gizycki, Hans Pharmaceuticals (Basel) Article The role of norethindrone acetate (NA) in the management of adenomyosis was evaluated with a retrospective chart review of 28 premenopausal women between 27–49 years of age presenting with moderate to severe pelvic pain and bleeding. Bleeding and dysmenorrhea scores were analyzed using paired T-tests. There was significant improvement of both dysmenorrhea and bleeding after treatment. Age showed no correlation with dysmenorrhea or bleeding. Low dose NA could be considered an effective, well-tolerated and inexpensive medical alternative to surgery for treating symptomatic adenomyosis. Large multicentric studies may help validate our findings. MDPI 2012-10-22 /pmc/articles/PMC3816659/ /pubmed/24281260 http://dx.doi.org/10.3390/ph5101120 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Muneyyirci-Delale, Ozgul
Chandrareddy, Ashadeep
Mankame, Siddhi
Osei-Tutu, Nanna
von Gizycki, Hans
Norethindrone Acetate in the Medical Management of Adenomyosis
title Norethindrone Acetate in the Medical Management of Adenomyosis
title_full Norethindrone Acetate in the Medical Management of Adenomyosis
title_fullStr Norethindrone Acetate in the Medical Management of Adenomyosis
title_full_unstemmed Norethindrone Acetate in the Medical Management of Adenomyosis
title_short Norethindrone Acetate in the Medical Management of Adenomyosis
title_sort norethindrone acetate in the medical management of adenomyosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816659/
https://www.ncbi.nlm.nih.gov/pubmed/24281260
http://dx.doi.org/10.3390/ph5101120
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